Rethinking sperm: lessons from mitochondrial function

  • Evelyn Bulkeley Department of Anatomy, Physiology, and Cell Biology School of Veterinary Medicine, University of California, Davis, CA
  • Azarene Foutouhi Department of Anatomy, Physiology, and Cell Biology School of Veterinary Medicine, University of California, Davis, CA
  • Stuart Meyers Department of Anatomy, Physiology, and Cell Biology School of Veterinary Medicine, University of California, Davis, CA
DOI: https://doi.org/10.58292/ct.v11.9941
Keywords: Sperm, mitochondrial function, oxidative phosphorylation, reactive oxygen species

Abstract

Biological nature of age-related declining fertility in males of any species, including stallions, has been elusive. In horses, economic costs to the breeding industry are frequently considered extensive. Mitochondrial function in ejaculated sperm, essential for sperm motility, is reflected by the dynamic processes of adenosine triphosphate production, mitochondrial oxidative efficiency and production of reactive oxygen species; this balance may become compromised in aging stallions and during cryopreservation process. This presentation will focus on mitochondrial integrity and function as an avenue for understanding the pathophysiology of sperm undergoing cryopreservation and male aging.

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Published
2019-09-01
How to Cite
Bulkeley E., Foutouhi A., & Meyers S. (2019). Rethinking sperm: lessons from mitochondrial function. Clinical Theriogenology, 11(3), 353-359. https://doi.org/10.58292/ct.v11.9941
Issue
Vol. 11 No. 3 (2019): September 2019 (Proceedings)
Section
Production Animal Session
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