Amorphus globosus
Keywords:
canine, dystocia, amorphus globosus, acardiac monster
Abstract
Amorphus globosus is a rare malformation that is defined as an acardiac asymmetrical rough spherical mass of tissue covered in skin. To authors’ knowledge, amorphus globosus has not been previously reported in canids. Herein, we describe amorphus globosus in an American Bulldog pup with accompanying radiograph, gross images, and histopathology. Additionally, a systematic review (preferred reporting items for systematic reviews and meta-analyses protocol) was performed for veterinary species; amorphus globosus has been reported in 22 bovids, 3 caprids, 1 ovid, and 1 equid.
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References
1. Anwar MT, Khan AI, Balasubramanian S, et al: A rare case of globosus amorphus in a goat. Can Vet J 2009;50:854–856.
2. Baghbadorani MK, Oghadam MF: Histological investigation and karyotyping of amorphous globosus cases occurred in a dairy herd throughout one year observation. Reprod Domest Anim 2017;52:100.
3. Citek J, Rehout V, Hajkova J: Congenital disorders in the cattle population of the Czech Republic. Czech J Anim Sci 2009;54:55–64. doi: 10.17221/1668-CJAS
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5. Duncan: Monstrosity in a cow – amorphous globosus. Vet J 1891;33:163–164. doi: 10.1016/S2543-3377(17)35545–0
6. Dunn HO, Lein DH. Kenney RM. The cytological sex of a bovine anidian (amorphous) twin monster. Cytogenetics 1967;6:412–419. doi: 10.1159/000129959
7. Shamseer L, Moher D, Clarke M, et al: Preferred reporting items for systemic review and meta-analysis protocols (PRISMA-P): elaboration and explanation. BMJ 2015;350:g7647. doi: 10.1136/bmj.g7647
8. Dunn HO, Roberts SJ. Chromosome studies of an ovine acephalic-acardiac monster. Cornell Vet 1971;62:425–431.
9. Fischer UR, Hofmeister B: Abnormal multiple pregnancy with septuplets in a cow a case report. Tierärztl Prax Ausg G Grosstiere Nutztiere 2018;41:253–256. doi: 10.1055/s-0038-1623180
10. Gehrke M, Blaszak B, Stachowiak M, et al: Amorphus globosus foetuses in Polish Holstein cattle: anatomical, histological, and genetic studies. J Vet Res 2019;63:391–398. doi: 10.2478/jvetres-2019-0057
11. Gobikrushanth M, Zachar EK, Singh N, et al: Theriogenology question of the month. J Am Vet Med Assoc 2022;260:170–173. doi: 10.2460/javma.21.06.0285
12. Hartigan PJ: An acardius amorphus from a cow. Irish Vet J 1972;26:133–136.
13. Hishinuma M, Hoshi N, Takahashi Y, et al: Vasculature and chromosomal composition in a bovine acardius amorphus. Jpn J Vet Sci 1988;50:1139–1141. doi: 10.1292/jvms1939.50.1139
14. Jena D, Khatti A, Singh SK, et al. Amorphous globosus in a cow: a case report. Theriogenol Insight 2017;7:79–81. doi: 10.5958/2277-3371.2017.00022.5
15. John D, Narasimhan KS: Amorphus globosus in a she goat. Cheiron 1980;9:129–131.
16. Kamimura S, Enomoto S, Goto K, at al: A globosus amorphus from an in vitro fertilized embryo transferred to a Japanese black cow. Theriogenology 1993;40:853–858. doi: 10.1016/0093-691X(93)90220-Y
17. Nascimento LC, Nakagaki KYR, Orlando DR, et al: Amorphus globosus in bovine. Arch Vet Sci 2013;18:19–20.
18. Pearson LK, Rodriguez JS, Tibary A: Theriogenology question of the month. J Am Vet Med Assoc 2011;238:1261–1263. doi: 10.2460/javma.238.10.1261
19. Purohit GN, Gupta AK, Gupta KA, et al: Amorphus globosus monster in a goat. Indian Vet J 2000;77:79.
20. Pushp MK, Purohit GN, Tripathi A, et al: Amorphus globosus monster removed by laparohysterotomy in a she buffalo – a case report. Theriogenol Insight 2015;5:153–156. doi: 10.5958/2277-3371.2015.00017.0
21. Singh AK, Brar PS, Pandey AK, et al: Amorphous globosus monster in a buffalo. Indian Vet J 2009;86:846–847.
22. Usta Z, Jacobsen B, Gottschalk M, et al: Amorphus globosus in a White Galloway cattle. Kafkas Univ Vet Fak Derg 2016;22:627–630.
23. Weber J, Rudolph N, Freick M: Facets of clinical appearance and aetiology in an unusual bovine amorphus globosus. Anat Histol Embryol 2017;46:502-506. doi: 10.1111/ahe.12286
2. Baghbadorani MK, Oghadam MF: Histological investigation and karyotyping of amorphous globosus cases occurred in a dairy herd throughout one year observation. Reprod Domest Anim 2017;52:100.
3. Citek J, Rehout V, Hajkova J: Congenital disorders in the cattle population of the Czech Republic. Czech J Anim Sci 2009;54:55–64. doi: 10.17221/1668-CJAS
4. Crossman JP, Dickens PSEM: Amorphus globosus in the mare. Vet Rec 1974;95:22. doi: 10.1136/vr.95.1.22-b
5. Duncan: Monstrosity in a cow – amorphous globosus. Vet J 1891;33:163–164. doi: 10.1016/S2543-3377(17)35545–0
6. Dunn HO, Lein DH. Kenney RM. The cytological sex of a bovine anidian (amorphous) twin monster. Cytogenetics 1967;6:412–419. doi: 10.1159/000129959
7. Shamseer L, Moher D, Clarke M, et al: Preferred reporting items for systemic review and meta-analysis protocols (PRISMA-P): elaboration and explanation. BMJ 2015;350:g7647. doi: 10.1136/bmj.g7647
8. Dunn HO, Roberts SJ. Chromosome studies of an ovine acephalic-acardiac monster. Cornell Vet 1971;62:425–431.
9. Fischer UR, Hofmeister B: Abnormal multiple pregnancy with septuplets in a cow a case report. Tierärztl Prax Ausg G Grosstiere Nutztiere 2018;41:253–256. doi: 10.1055/s-0038-1623180
10. Gehrke M, Blaszak B, Stachowiak M, et al: Amorphus globosus foetuses in Polish Holstein cattle: anatomical, histological, and genetic studies. J Vet Res 2019;63:391–398. doi: 10.2478/jvetres-2019-0057
11. Gobikrushanth M, Zachar EK, Singh N, et al: Theriogenology question of the month. J Am Vet Med Assoc 2022;260:170–173. doi: 10.2460/javma.21.06.0285
12. Hartigan PJ: An acardius amorphus from a cow. Irish Vet J 1972;26:133–136.
13. Hishinuma M, Hoshi N, Takahashi Y, et al: Vasculature and chromosomal composition in a bovine acardius amorphus. Jpn J Vet Sci 1988;50:1139–1141. doi: 10.1292/jvms1939.50.1139
14. Jena D, Khatti A, Singh SK, et al. Amorphous globosus in a cow: a case report. Theriogenol Insight 2017;7:79–81. doi: 10.5958/2277-3371.2017.00022.5
15. John D, Narasimhan KS: Amorphus globosus in a she goat. Cheiron 1980;9:129–131.
16. Kamimura S, Enomoto S, Goto K, at al: A globosus amorphus from an in vitro fertilized embryo transferred to a Japanese black cow. Theriogenology 1993;40:853–858. doi: 10.1016/0093-691X(93)90220-Y
17. Nascimento LC, Nakagaki KYR, Orlando DR, et al: Amorphus globosus in bovine. Arch Vet Sci 2013;18:19–20.
18. Pearson LK, Rodriguez JS, Tibary A: Theriogenology question of the month. J Am Vet Med Assoc 2011;238:1261–1263. doi: 10.2460/javma.238.10.1261
19. Purohit GN, Gupta AK, Gupta KA, et al: Amorphus globosus monster in a goat. Indian Vet J 2000;77:79.
20. Pushp MK, Purohit GN, Tripathi A, et al: Amorphus globosus monster removed by laparohysterotomy in a she buffalo – a case report. Theriogenol Insight 2015;5:153–156. doi: 10.5958/2277-3371.2015.00017.0
21. Singh AK, Brar PS, Pandey AK, et al: Amorphous globosus monster in a buffalo. Indian Vet J 2009;86:846–847.
22. Usta Z, Jacobsen B, Gottschalk M, et al: Amorphus globosus in a White Galloway cattle. Kafkas Univ Vet Fak Derg 2016;22:627–630.
23. Weber J, Rudolph N, Freick M: Facets of clinical appearance and aetiology in an unusual bovine amorphus globosus. Anat Histol Embryol 2017;46:502-506. doi: 10.1111/ahe.12286
Published
2024-02-16
How to Cite
McNulty K., Jaffe M., & Yi J. (2024). Amorphus globosus. Clinical Theriogenology, 16. https://doi.org/10.58292/ct.v16.10328
Issue
Section
Case Reports
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