Canine nomograph evaluation improves puppy immunization

  • Laurie Larson Companion Animal Vaccine and Immuno Diagnostics Service Laboratory Department of Pathobiological Sciences University of Wisconsin School of Veterinary Medicine Madison, WI
  • Bliss Thiel Companion Animal Vaccine and Immuno Diagnostics Service Laboratory Department of Pathobiological Sciences University of Wisconsin School of Veterinary Medicine Madison, WI
  • Vanessa Santana Companion Animal Vaccine and Immuno Diagnostics Service Laboratory Department of Pathobiological Sciences University of Wisconsin School of Veterinary Medicine Madison, WI
  • Ronald Schultz Companion Animal Vaccine and Immuno Diagnostics Service Laboratory Department of Pathobiological Sciences University of Wisconsin School of
Keywords: Canine, nomograph, titer, vaccination, distemper, parvovirus

Abstract

Immunization failure in puppies by modified live vaccines for canine distemper virus and canine parvovirus can occur due to interference from maternally derived antibody. Quantitative measurement of specific antibody (via half-life degradation analysis; nomograph) is available to determine passive transfer from dam. Nomograph enables vaccination timing and followup titer testing tailored for each litter. Objective was to evaluate effectiveness of this approach and use of a nomograph. Puppies (506 puppies < 1 year) that had nomograph completed for their dam were not different in protection rate compared to vaccinated adults and were proven immune at 15.9 weeks. A cohort of similar puppies at 21.6 weeks that did not have nomograph completed for their dam was more likely to have not responded to vaccination.

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Published
2020-09-01
How to Cite
Larson L., Thiel B., Santana V., & Schultz R. (2020). Canine nomograph evaluation improves puppy immunization. Clinical Theriogenology, 12(3), 216-221. Retrieved from https://clinicaltheriogenology.net/index.php/CT/article/view/9233
Issue
Vol. 12 No. 3 (2020): September
Section
Papers
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