Sperm acrosome associated 3 protein expression in equine primordial, primary, secondary, and tertiary follicles

  • Brynley Cozzi Department of Animal and Rangeland Sciences, College of Agricultural Science Oregon State University, Corvallis, OR
  • Zahra Kiesler Department of Animal and Rangeland Sciences, College of Agricultural Science Oregon State University, Corvallis, OR
  • Michelle Kutzler Department of Animal and Rangeland Sciences, College of Agricultural Science Oregon State University, Corvallis, OR
DOI: https://doi.org/10.58292/therio.v13i.9100
Keywords: Granulosa cell, horse, ovary, sperm acrosome associated 3 protein

Abstract

Granulosa cellThe objective of this study was to characterize the protein expression of sperm acrosome associated 3 (SPACA3) in the equine ovary. Formalin-fixed and paraffin-embedded ovarian sections from 16 horses were processed for routine immunohistochemistry for SPACA3. Representative images were digitally captured at 400 x magnification. In all mares, SPACA3 was expressed in granulosa cells of all stages of follicles. Expression of SPACA3 in all equine follicular stages suggests that this may be a permanent immunosterilant target for the management of feral horse herds. Additional research is needed to determine if horses can produce a robust humoral response to a SPACA3 vaccine to induce sustained infertility.

Downloads

Download data is not yet available.
Published
2021-06-01
How to Cite
Cozzi B., Kiesler Z., & Kutzler M. (2021). Sperm acrosome associated 3 protein expression in equine primordial, primary, secondary, and tertiary follicles. Clinical Theriogenology, 13(2), 85-88. https://doi.org/10.58292/therio.v13i.9100
Issue
Vol. 13 No. 2 (2021): June
Section
Research Reports
Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Authors retain copyright of their work, with first publication rights granted to Clinical Theriogenology. Read more about copyright and licensing here.