A case of impaired fertility in a Large White boar with sex chromosome chimerism

  • Joaquin Paredes Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada
  • Lauren Lambert Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada
  • Lukasz Czochara Karyotekk Incorporated, Guelph, ON, Canada
  • Patrick Charagu Hypor Incorporated, Regina, SK Canada
  • Darren Griffin School of Biosciences, University of Kent, Canterbury, UK
  • Megan Magee Karyotekk Incorporated, Guelph, ON, Canada
  • Laura Favetta Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada
  • Allan King Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada; and Karyotekk Incorporated, Guelph, ON, Canada
  • Daniel Villagomez Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada; and Departamento de Producción Animal, Universidad de Guadalajara, Zapopan, Mexico
DOI: https://doi.org/10.58292/CT.v16.10690
Keywords: Male pigs, chromosomal abnormalities, subfertility

Abstract

Chromosomal abnormalities are a well-established cause of fertility impairment in domestic animals. Chromosomal abnormalities in pigs may result in low prolificacy and subsequent reduction in reproductive parameters (e.g. litter sizes and nonreturn rates) having substantial impact on swine industry. Until now, the effect of sex chromosome abnormalities on fertility has not been thoroughly documented for male pigs. We report a case study involving a Large White boar with sex chromosome chimerism (2n = 38, XX/XY) identified by conventional karyotyping and fluorescence in-situ hybridization. Progeny of this boar was evaluated; there was reduction (p < 0.001) in litter size demonstrating the potential impact of sex chromosome chimerism on herd productivity in pigs.

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Published
2024-08-29
How to Cite
Paredes J., Lambert L., Czochara L., Charagu P., Griffin D., Magee M., Favetta L., King A., & Villagomez D. (2024). A case of impaired fertility in a Large White boar with sex chromosome chimerism. Clinical Theriogenology, 16. https://doi.org/10.58292/CT.v16.10690
Issue
Vol. 16 (2024)
Section
Case Reports
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